AsSmurfsgetreadyfortheBlueMoonFestival,PapaSmurfseesinhiscauldronavisionofClumsySmurfreachingforadragonwandandtheSmurfsincageswhileGargamellaughs.Notwantingthisvisiontocometrue,PapaSmurfrefusestoallowClumsytopickSmurfRoots,butClumsydisobeysPapaSmurfandendsupunintentionallyleadingGargamelandAzraeltothevillage.TheSmurfsallfleefortheirliveswhileClumsyunknowinglyrunstowardstheForbiddenFalls,withPapaSmurf,Smurfette,Grouchy,BrainyandGutsyrunningafterhim.Theyfindhimattheedgeofacliff,andwhiletryingtohelphimup,theyaresuckedintoagiganticvortexthatspiritsthemtopresentdayNewYorkCity.Tomakemattersworse,GargamelandAzraelfollowandtheSmurfsendupintheapartmentofPatrickandGraceWinslow,amarriedandexpectantcoupleandtheirBassetHoundElway.Afterclarifyingthings,theWinslowsbefriendthemandallowthemtostayintheirapartment.Thenextday,needingtofinda"stargazer",theSmurfsfollowPatricktohisworkplaceatAnjelouCosmeticsbeforehecallsGracetopickthemup. 　　However,havingextracted"Smurfessence"fromalockofSmurfette'shair,GargamelalsoarrivesandendsupbeingtreatedbyPatrick'sbossOdileuponusingmostofhisacquiredmagictoturnhermotheryoung.ButGargamelresumeshissearchuponrecognizingPatrickandfollowinghimtothetoystorewheretheSmurfsranintoafterfindingtheirstargazer,atelescope.TheWinslowsmanagetosavetheSmurfsfromboththechildrenwantingthemandGargamel,whoendsupbeingsenttojailbeforehemanagestobustoutwiththeaidofhouseflies.Bythattime,PapaSmurfmanagestocalculatethenightheandtheotherscangethome.Butfirst,hemustfigureoutthespelltodoso.PatricktellsthemthatthereisanoldbookstoreinthecitynearAnjelouCosmeticsashebondswiththeSmurfsaftersendingwhathebelievedtobehisfinishedadvertisementtobepublished.However,thenextday,PatricklearnsthatClumsyaccidentallyattachedablue-moonthemedsideprojectandheloseshistemperbeforewalkingoutonboththeSmurfsandGracetosavehisjob. 　　Forcedtosearchontheirown,theSmurfsfindthestoreandfindthebookL’HistoiredeSchtroumpfsbyresearcherPeyo,containingthespelltoturnthemoonblue.Butlearningoftheirlocation,GargamelsneaksintothebookstoreandfindsthedragonwandfromPapaSmurf'svision,transferinghismagicintoitasheusesittocapturePapaSmurfashesendstheotherstosafety.ThoughtheSmurfspromisedPapaSmurfthattheywon'ttrytosavehimandreturnhome,ClumsyandPatrick,havingsawtheerrorofhisactions,convincethemtoplanarescue.AtBelvedereCastle,afterincreasingthedragonwand'spowerwithbitsofPapaSmurf'sbeard,GargamelfindshimselffacingalltheSmurfsthatweresummonedtoNewYorkbyBrainyconjuringthebluemoon.AstheSmurfarmybattlesGargamel,SmurfettefightsAzraelandsavesPapaSmurfbeforetheyjointhefray.ThoughGargamelattemptstobreaktheSmurfsbykillingoffPapaSmurf,PatricksavehimwhileGutsyknocksthedragonwandoutofthewizard'shand.Clumsytriestocatchit,andtoPapaSmurf'ssurprise,managestocatchitandsendGargamelflyingintoatrashcanandbeinghitbyabuswiththeadvertisement"BlueMoon"withitbeforePapaSmurfbreaksit.Soonafter,theSmurfstaketheirleaveasPatrickreceivesacallfromOdilethathestillhashisjob.Later,whilePatrickandGracehaveababyboy,whomtheynameBlue